We are currently seeking highly motivated and talented graduate students and postdoctoral researchers, as well as a technician, to join our dynamic team at Yun Lab.

Ideal postdoctoral candidates should have a solid publication record in relevant fields, such as physics, chemistry, bioengineering, and possess excellent communication skills and a strong work ethic.

 

To apply, please submit a comprehensive CV and a cover letter to Prof. Yun at syun@hms.harvard.edu. Recommendation letters are not required for initial inquiries but will be necessary for full consideration.

 

 

Project 1: Intravital Imaging of Immune Cells and Responses after Vaccination

 

This NIH-funded project, in collaboration with Dr. Thomas Kupper at BWH and Dr. Charles Lin at MGH, aims to visualize the behavior and function of T cells within the lung and skin in mouse models of skin vaccination using intravital fluorescence microscopy. We are looking for a postdoc with experience in intravital imaging of immune cells. Excellent communication skills and project coordination experience are required.

 

 

Project 2: High-speed Flow Sorting of Laser-barcoded Cells and Biological Assays

 

The Yun Lab has pioneered the development of Laser Particles (LPs), semiconductor nanoparticles that emit single-mode laser spectra. We are currently exploring their innovative applications in life sciences. LPs offer bright, spectrally narrowband emissions, making them suitable for use as cellular barcodes and building blocks for multiplexed bead assays. We are looking for a highly motivated and capable researcher for a project with three specific aims:

 

1.     Construct a high-speed flow sorter for selecting LPs with specific spectra or sorting cells containing certain LPs.

2.     Fabricate a large color palette of LPs using the sorting instrument.

3.     Apply multi-color LPs for multiplexed assays.

 

The ideal candidate should have experience in constructing microfluidic and optical systems and working with cells and biological samples.

 

 

Project 3: Multidimensional Single-Cell Analysis from Live Imaging to Sequencing

 

Funded by the NIH Director's Transformative Award, this project aims to advance single-cell analysis through novel cell-barcoding technologies. The project's primary goal is to move beyond static analysis by incorporating additional dimensions, such as spatiotemporal changes and cell interactions. We are developing innovative DNA-optical barcodes that enable time-lapse live-cell imaging and high-throughput single-cell sequencing, which can then be aligned to the same cells unambiguously according to their individual cell barcodes. The ideal candidate should have a strong interest in pioneering research, new technologies, and demonstrated expertise in cellular experiments and sequencing and imaging data analysis.

 

 

In addition, we welcome applications from exceptional candidates eager to explore new ideas and projects. For instance, we are particularly interested in the development and applications of Brillouin microscopy, as well as innovative light sources, such as nanolasers.

 

 

Last updated on February 1, 2025